Editorial: Upping the Stakes

Upping the Ante

One-upping the LD50.

Proliferative lesions in the livers of mice treated 18 months previously with cisplatin Sir-Cis-diammine-dichloroplatinum II ('cisplatin') is a widely used cytotoxic agent that is known to cause long-term renal insufficiency. Bulger and Dobyan (1984) and Dobyan (1985) have reported hyperplastic lesions in the kidneys of rats treated 6 and 15 months previously with a single intraperitoneal dose ...

Neil Poulter: upping the pressure on hypertension.

Visiting Neil Poulter at the International Centre for Circulatory Health (ICCH), which he co-directs in the west London district of White City, it might seem he’s based in one of the less exalted outposts of the centre’s parent body, Imperial College London. Not so. Poulter’s ICCH office is part of what will eventually be home to a major expansion of the college. This will incorporate new centr...

Upping the game for OR cleaning with monitoring and partnerships.

The Greenhouse Stakes of Globalization